Cardiac Progenitor Cells Enhance Neonatal Right Ventricular Function After Pulmonary Artery Banding
نویسندگان
چکیده
منابع مشابه
effects of cardiac rehabilitation program on right ventricular function after coronary artery bypass graft surgery
background: cardiac rehabilitation has been recognized as one of the most effective strategies for managing cardiovascular indices as well as controlling the cardiovascular risk profile, in particular after coronary artery bypass graft surgery (cabg). however, the effect of this program on right ventricular function following cabg is unclear. the aim of this study was to evaluate the impact of ...
متن کاملRight ventricular hypertrophy and apoptosis after pulmonary artery banding: regulation of PKC isozymes.
OBJECTIVE Pressure overload induced by pulmonary artery banding (PAB) leads to right ventricular (RV) hypertrophy and cardiomyocyte apoptosis. The present study was performed to investigate whether protein kinase C isozymes (PKC-alpha, PKC-betaI, PKC-betaII, PKC-delta and PFC- epsilon ), calcineurin and the renin-angiotensin system (RAS) contribute to PAB-induced cardiac remodeling. METHODS A...
متن کاملRight and left ventricular function after chronic pulmonary artery banding in rats assessed with biventricular pressure-volume loops.
In many patients with congenital heart disease, the right ventricle (RV) is subjected to abnormal loading conditions. To better understand the state of compensated RV hypertrophy, which could eventually progress to decompensation, we studied the effects of RV pressure overload in rats. In the present study, we report the biventricular adaptation to 6 wk of pulmonary artery banding (PAB). PAB re...
متن کاملPulmonary artery banding for ventricular septal defect.
It is well known that there is a very high mortality in children with ventricular septal defect, who develop heart failure in early infancy (Marquis, 1950; Boesen and Vendel, 1955). Morgan, Griffiths, and Blumenthal (1960) reviewed 125 children up to 14 years of age with ventricular septal defect. Of these, 17 developed heart failure in the first six months of life, 10 dying before their first ...
متن کاملRight ventricular targeted gene transfer of a beta-adrenergic receptor kinase inhibitor improves ventricular performance after pulmonary artery banding.
OBJECTIVE Abrupt increases in right ventricular afterload occur after cardiac transplantation and pulmonary artery banding, which can result in right ventricular hypertrophy and dilatation. Right ventricular dysfunction is also accompanied by beta-adrenergic receptor desensitization. We sought to determine whether selective right ventricular expression of a transgene encoding a beta-adrenergic ...
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ژورنال
عنوان ژورنال: The Annals of Thoracic Surgery
سال: 2017
ISSN: 0003-4975
DOI: 10.1016/j.athoracsur.2017.04.058